The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.
No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...
Researchers have created the most comprehensive map to date of DNA elements that regulate gene activity, nearly tripling the ...
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Gene therapy for sickle cell and β-thalassemia works by disrupting three-dimensional genome structure
Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...
A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...
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