Male inbred Brown Norway rats were obtained from Harlan-CPB (Austerlitz, the Netherlands), weighing 250–300 g and were fed a standard laboratory diet ad libitum (Hope Farms Woerden, the Netherlands).

Background A 35-year-old man with alcoholic cirrhosis, ascites and alcoholic hepatitis presented with new-onset renal insufficiency of unclear etiology after recovery from an episode of ...

Do you have a maximum dose for inotropes (eg, 2 mcg/kg/min for noradrenaline)? Also, if you have invasive monitoring for a septic patient, eg, pulmonary artery (PA) catheter, would you push up your ...

DRAMATIC ADVANCES IN THE MANAGEMENT of erectile dysfunction have occurred over the past decade. Oral therapy with vasoactive agents has emerged as first-line treatment and has transformed both the ...

In children with septic shock without known cardiac dysfunction, initial treatment with norepinephrine was associated with a lower 30-day mortality but similar rates of major adverse kidney events by ...