Week 10 of the NFL season kicks off with an AFC West showdown on Thursday night as the Denver Broncos host the Las Vegas Raiders. And that's just the start of the division rivalry slate this week. The Cardinals will hope this is finally the week Kyler Murray returns to the starting lineup after a foot injury kept him limited ahead of Week 9.

Does that mean you should immediately jump on the Jets with Week 10 NFL picks as they host the Browns? New York just dealt away arguably its two best players at the trade deadline, which shifted the Week 10 NFL odds from the Jets being favored by 1.

Who is favored in the Thursday Night Football game between the Las Vegas Raiders and Denver Broncos? What about the Sunday Night Football game between the Pittsburgh Steelers and Los Angeles Chargers?

Get the opening NFL Week 10 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Nov. 6, 2025.

NFL Week 9 is here, so let's look at the odds and make some picks and predictions for the next weekend of the 2025 regular season.

It's another busy week with 30 teams in action in Week 9 of the NFL season. On Thursday ... For most current odds go to ESPN BET Las Vegas Raiders vs. Cincinnati Bengals-7 Money Line: Raiders (+270) ; Bengals (-340) Total: 46.5; Opened: 45.5 FPI favorite ...

SportsLine expert Jeff Hochman breaks down his top money line parlays for favorites and underdogs for Week 9 of the NFL season

Monday Night Football delivers another primetime showdown to end Week 9 in the NFL. The Arizona Cardinals (2-5) have lost their last five games as they face the Dallas Cowboys (3-4-1).  DraftKings Sportsbook is making this MNF duel exciting with their promo offer.