Many icosahedral viruses assemble proteinaceous precursors called proheads or procapsids. Proheads are metastable structures that undergo a profound structural transition known as expansion that ...
The drug can be produced for as little as $25 per person annually, but even at $2000 per person, it can reduce new US infections almost entirely, a researcher says.
Researchers are using DNA 'origami' templates to control the way viruses are assembled. The global team behind the research developed a way to direct the assembly of virus capsids -- the protein shell ...
Griffith University researchers have played a key role in using DNA 'origami' templates to control the way viruses are assembled. The global team behind the research, published in Nature ...
In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination. Study: First-in-human ...
NEW YORK & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Apertura Gene Therapy, a biotechnology company opening opportunities in genetic medicine for treating debilitating diseases with limited options, today ...
Coarse-grained simulations of HK97 genome packaging. A motor protein pushes DNA through a portal into the capsid, where the DNA coils into switchback loops. DNA is colored in order of entry into the ...
In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...
The FDA granted priority review, with a decision expected by June 19, 2025. LEN represents a novel class of HIV therapies by targeting the viral capsid, a multifunctional protein essential for HIV ...
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