Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

Radiation from nail dryers may damage DNA and cause cancer-causing mutations in human cells, a study has found - and that might have you wondering whether your regular gel mani-pedi is worth the risk.

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Mitochondria are incredible organelles. They not only provide crucial power to our cells, these little machines also have ...

The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers ...

Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists from the German Cancer Research Center (DKFZ) and the Universities of Cambridge and ...