Studies of recombination and how it varies depend crucially on accurate recombination maps. We propose a new approach for constructing high-resolution maps of relative recombination rates based on the ...

When the genomes of parents come together to create the genome of a child, their DNA recombines; similar parts are rearranged so that a child carries sections of their parents genomes that have been ...

Quantum Dot (QD) is a nanometer-sized semiconductor nanocrystal that has unique optical properties such as the ability to emit light in the range of optical frequencies depending on its size. QDs have ...

DSBs are more likely to occur in some genomic regions than others. Elucidating mechanisms shaping the DSB “landscape” requires identifying the biochemical factors involved, understanding how they ...

How does DNA maintain its original form? DNA carries a vast quantity of genetic information and continuation of species depends on accurate duplication of the DNA. This duplication process, called DNA ...

Researchers have quantified one of the most important and hard-to-measure phenomena in molecular evolution: the effect of genetic recombination on a species' capacity of adaptation. UAB researchers ...

RNA-Based Homologous Recombination Deficiency Signature Detects Homologous Recombination Deficiency-RNA+ Patients With and Without Homologous Recombination Repair Gene Pathogenic Alterations in Men ...

New studies underscore how coronaviruses frequently mix their genetic components — which could contribute to the rise of dangerous variants. By Roxanne Khamsi In recent weeks, scientists have sounded ...

Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma Surrogate readouts of HRD identify a greater proportion of patients with ...

Among patients with prostate cancer with homologous recombination repair mutations (HRRm) receiving Akeega (niraparib and ...

In females, meiosis is initiated during fetal development. Digital micrographs of fetal ovary at embryonic day 14.5 hybridized to the antisense Spo11 probe are shown here in panels a and b. — Dark ...