Buffalo, which is the No. 6 seed in the AFC playoff picture, is nearly a lock to make the postseason and have a clear path to pluck the AFC East title. The Bills trail the Patriots by one game with three games to play.

Josh Allen led a stunning 35-10 rally after falling behind 21-0, keeping Buffalo's AFC East title hopes alive while climbing in multiple NFL power rankings.

As with their Week 15 matchup in Foxborough, MA, the Bills enter Week 16 as a road favorite over their AFC opponent. Where last week’s odds represented a lot of uncertainty out of bettors, this week’s numbers tell of a different story expected to unfold on the southern Ohioan shore of Lake Erie when Buffalo takes on the Cleveland Browns (3-11).

When the Patriots return from their bye week they'll have a chance to win the AFC East, with a 'hat and t-shirt game' against the Bills.