Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

SAR11 bacteria dominate the world’s oceans by being incredibly efficient, shedding genes to survive in nutrient-poor waters.

"By cleverly combining new techniques for analyzing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia," predicts Professor John ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...