A randomized phase 2 maintenance strategy with cabozantinib 60 mg daily for up to 2 years failed to improve 4-month PFS versus placebo in high-grade uterine sarcomas. Median PFS was identical at 3.7 ...
Mesothelin-targeted CAR-NKT cells leveraged three recognition mechanisms, potentially limiting antigen escape and immunoediting compared with single-pathway CAR-T constructs. Complete tumor ...
Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival ...
HHV-8 infection is necessary but insufficient for KS; clinically significant disease most often emerges with substantial immunosuppression, including HIV infection or iatrogenic post-transplant states ...