Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Researchers headed by a team at the University of California, Irvine, Joe C. Wen School of Population & Public Health have built what they suggest is the first cell type-specific gene regulatory ...

Meghan Brady, Ralph McNeilage, Meghan McLean Poon Ph.D. Current Overview: Genetically engineered (GE) organisms in the United States are subject to regulation from the EPA for environmental concerns, ...

Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & Public Health have created the most detailed maps to date showing how genes ...

After facing a delayed decision deadline and a clinical hold, Regenxbio’s Hunter syndrome gene therapy has been rejected by the FDA. In rejecting RGX-121, the FDA raised concerns about its clinical ...

Aurora Therapeutics' first target is the rare inherited disease phenylketonuria, also known as PKU. Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013 ...

The bill, which lawmakers passed in June, will be modified to more closely match a similar law in California, at Big Tech’s urging. By Benjamin Oreskes Gov. Kathy Hochul of New York signed legislation ...

An R-loop is a three-stranded nucleic acid structure that serves as a transcriptional intermediate, consisting of an RNA-DNA hybrid and a displaced single-stranded DNA (ssDNA). Small RNAs are RNA ...

Research links variations in the gene GRIN2A to a higher risk of developing schizophrenia and other forms of mental illness. The GRIN2A gene regulates communication between neurons by producing the ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...