A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 -- the most prevalent form of adult-onset muscular dystrophy -- provides insight into why patients develop fatty liver ...

Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

The ketogenic diet has been sold as a shortcut to weight loss, sharper focus, and better blood sugar control. A new long-term ...

This dark chasm looks like a hole in the center of a brightly colored tapestry, but it’s actually a central vein in the liver of a mouse. The liver is like a very efficient sewage treatment plant for ...

Liver disease, due to viral infections, alcohol abuse, obesity, or cancer, accounts for 1 in every 25 deaths worldwide. A liver transplant can be life saving for people with end-stage liver disease.

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection. A study led by researchers at the University of ...

A team of researchers has discovered that inhibiting a liver enzyme called ACMSD can supercharge NAD+ levels, protecting the liver from inflammation, scarring, and DNA damage in models of fatty liver ...