One such chemical modification is cytidine acetylation (N4-acetylcytidine). Until now, the precise function of this chemical modification within cells has not been clearly understood. In particular, ...

SAN DIEGO--(BUSINESS WIRE)--Alida Biosciences (AlidaBio), an innovator in epigenomic research tools, today announced the full commercial launch of its EpiPlex™ platform, the first to concurrently ...

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators. The ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message (mRNA), which is then converted into a protein. Although DNA remains the same ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

New research published today in Nature from Ryan Flynn, MD, PhD, in collaboration with Vijay Rathinam, DVM, PhD, and his graduate student Vincent Graziano at UConn Health and other colleagues at ...

To overcome these limitations, the research team developed a "targeted RNA acetylation system (dCas13-eNAT10)" by combining Cas13, gene scissors that precisely target desired RNA, with a hyperactive ...