Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial ...

When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type ...

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch. Their knot-like ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

A new study led by Rice University's Pernilla Wittung-Stafshede has revealed that protein clumps, or plaques that clog the brain, associated with Parkinson's disease are not merely waste; they can ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can ...