Background Gastric cancer (GC) ranks among the most prevalent lethal tumours globally. Cancer-associated fibroblasts (CAFs) are pivotal in creating an immunosuppressive tumour microenvironment (TME) ...

5 Catholic Kwandong University College of Medicine Department of Medical Science, Gangneung-si, The Republic of Korea Background Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been reported to ...

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We thank Drs Fujisawa and Fujikawa for their thoughtful comments, which highlight professional and organisational determinants that complement our data on waste generation.1 2 In our multicentre study ...

Background Faecal microbiota transplantation (FMT) is a novel form of therapeutic manipulation through gastroscopy, colonoscopy, naso-intestinal tube, et al, which brings pain and inconvenience to the ...

We read with great interest the article by Adams et al in *Gut* on the development and validation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) score to ...

Background Covid-19 Induced Hepatitis (CIH), is a novel terminology which is used in this article for the first time in the medical literature. Objective To study the pattern of liver impairment in ...

Introduction Transcriptional analyses have identified several distinct molecular subtypes in pancreatic ductal adenocarcinoma (PDAC) that have prognostic and potential therapeutic significance.

2 Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan 3 Department of Internal Medicine, GI Unit, Massachusetts General Hospital, Boston, Massachusetts, USA 4 ...

Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...

2 Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, People’s Republic of China Objective Immune checkpoint blockade (ICB) has improved cancer ...

BACKGROUND Crohn's disease is a heterogeneous disorder with both a genetic and environmental aetiology. Clinical classifications of the disease, such as the newly proposed Vienna classification, may ...