The global pandemics of plague and smallpox in the Middle Ages claimed hundreds of millions of lives. In this era, long before the concepts of pathogens and infectious diseases were established, ...

Anticoagulation is a critical component in the treatment of cardiovascular diseases. Large randomised controlled trials have ...

International Centre for Circulatory Health, 10th Floor QEQM Wing, St Mary’s Hospital, and Imperial College Paddington and Clinical Pharmacology, NHLI, Imperial College of Science, Technology & ...

In 2017, the British Association for Cardiovascular Prevention and Rehabilitation published its official document detailing standards and core components for cardiovascular prevention and ...

Atrial fibrillation (AF) is the most common arrhythmia and is a leading cause of stroke and heart failure yet often remains undiagnosed. Screening has been proposed to identify asymptomatic AF and ...

Obesity is an independent driver of cardiovascular disease (CVD), mediated through adverse haemodynamic loading, insulin resistance, systemic inflammation, endothelial dysfunction and prothrombotic ...

6 Institut für Medizinische Statistik und Epidemiologie, Technical University of Munich, Munich, Germany Objective The optimal treatment of patients with acute and severe decompensation of aortic ...

1 King's College London British Heart Foundation Centre of Research Excellence, The Rayne Institute, St. Thomas’ Hospital Campus, London, UK 2 National Institute for Health Research Biomedical ...

Background Coronary microvascular dysfunction (CMD) is associated with a poor prognosis but is difficult to diagnose non-invasively. In a recent paper, ST-segment depression on exercise-ECG was found ...

Background Drug exposure has been reported in association with Takotsubo syndrome, but the breadth and relative strength of these reporting signals across therapeutic classes remain incompletely ...

Background Socioeconomic disparities are associated with sudden cardiac arrest (SCA) in older populations, but evidence in young adults is limited. We investigated the association between income ...

Introduction Cardiovascular benefits deriving from physical activity are well known, but it is unclear whether physical activity trajectories in late life are associated with different risks of ...