Vladimir Shulaev | Author | LCGC International provides separation science insights, including liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS).

Cardinal Health discusses with LCGC International how switching from reversed-phase to hydrophilic interaction liquid chromatography (HILIC) can unmask a hidden excipient artifact mistaken for a true ...

He describes how labs often receive samples with vague instructions to simply "find out what PFAS are in it," when what's ...

Melissa Dunkle, senior research scientist at Dow Benelux BV, The Netherlands, explores practical aspects of using multidimensional pyrolysis gas chromatography (Pyr-GCxGC) to investigate fluoropolymer ...

Bryan Vining introduces one of the most persistent problems in per- and polyfluoroalkyl substances (PFAS) work: background contamination. Because PFAS compounds are so ubiquitous, he notes, measuring ...

Bryan Vining notes that early PFAS concern centered on eight-carbon compounds like perfluorooctanoic acid (PFOA) and ...

Technique selection hinges on volatility/polarity; LC‑HRMS typically initiates characterization for nonvolatile/semi-volatile features, while GC‑MS can resolve ...

LC-MS/MS identified chlortetracycline in 1/29 and doxycycline in 4/29 chicken-based cat kibbles, indicating sporadic antibiotic carryover into finished commercial diets. PFAS were detected in 7/29 ...

uMRM links untargeted MS/MS acquisition to quantitative workflows, prioritizing experimentally derived fragmentation over purely in silico predictions. Empirical controls and noise-filtering ...

Shimadzu expanded its eTOC portfolio with the TOC-1000e S to continuously quantify trace organic contamination in ultrapure ...