Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Meghan Brady, Ralph McNeilage, Meghan McLean Poon Ph.D. Current Overview: Genetically engineered (GE) organisms in the United States are subject to regulation from the EPA for environmental concerns, ...

Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & Public Health have created the most detailed maps to date showing how genes ...

Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning model PARM. This might bring an end to a scientific mystery: how genes know ...

The Senate Agriculture Committee on Thursday voted to advance its version of a crypto market structure bill in a party-line vote. The development marks the first time crypto market structure ...

Aurora Therapeutics' first target is the rare inherited disease phenylketonuria, also known as PKU. Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013 ...

Abstract: Biological and biomedical knowledge graphs can be disparate in their design when a standard has not been widely accepted by the community, even more when they represent data from a ...

DNA just revealed a hidden operating system—and it doesn’t look like a helix. Scientists have created the first comprehensive map of DNA quadruplexes, fleeting knot-like structures that play an ...

Fine-tuning a gene centrally involved in regulating the immune system offers potential clues for future autoimmunity and cancer treatments. The immune system faces a delicate balancing act: it must be ...

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein ...