Autoimmune and autoinflammatory diseases are distinct but related categories of disorders characterized by an abnormal immune response. While autoimmune diseases involve adaptive immunity and the ...

Select the journal/section where you want your idea to be submitted: This is the second volume of our previous collection, linked here. Mental health disorders and physical diseases often co-occur, ...

Sickle cell disease—the subject of a new Seminar in The Lancet—is one of the most prevalent and fastest-growing genetic disorders worldwide. Although its true prevalence is difficult to determine ...

For over a hundred years, the specter of a schizophrenia diagnosis has frightened patients and their families. Yet it confers ...

Researchers identify a repeat expansion in the GOLGA8A gene as a major genetic driver for a rare, early-onset form of frontotemporal dementia.

Researchers at VIB and Antwerp University have identified a major genetic risk factor for a rare form of frontotemporal ...

Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and ...

Researchers developed brain organoids from patient samples to model genetic subtypes of autism spectrum disorders (ASD), creating a translational platform that better reflects the human-specific ...

Scientists have uncovered the oldest known genome of the bacterium responsible for syphilis, revealing a previously unknown lineage that existed thousands of years ago in the Americas.

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

A new method for safely inserting large chunks of DNA into genomes has now measured up in mice, potentially paving the way ...

This year’s Rare Disease Day event Feb. 27 at the Jacobs School of Medicine and Biomedical Sciences focused on updates in research and diagnostics, and advancements in treatment.