Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus.

Inside each of your cells lies a nucleus, its master command center. Protected inside each nucleus are your chromosomes, ...

Michael Rout, the George and Ruby deStevens Professor and head of the Laboratory of Cellular and Structural Biology at ...

Cell karyotype exhibiting trisomy: A conceptual image of a cell karyotype exhibiting trisomy, three copies of one chromosome. Credit: NIH – CC BY-NC 2.0 via Flickr. A team of researchers has generated ...

Cells are the basic building blocks of life—the smallest units that can do all the jobs a living thing needs. Most cells fit into two groups: prokaryotes and eukaryotes. The most significant ...

Human eggs made from a volunteer’s skin DNA were fertilized in the lab on September 30, 2025, and some grew for nearly a week. A peer-reviewed study reports that early embryos formed, although most ...

The method could one day become a treatment for infertility A decade of further research needed, scientists say The process overcomes an obstacle that stymied previous attempts Significant safety ...

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos. The ...

Early lab work shows reprogrammed skin cells can yield embryos, hinting at future infertility solutions but raising safety questions that demand more study. Infertility affects millions of people ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Objective. The arrangement of chromosomes in the cell nucleus has implications for cell radiosensitivity. The development of new tools to utilize Hi-C chromosome conformation data in nanoscale ...