ALZFORUM

12 Phosphorylation-Mimicking Mutations Twist Tau into AD Filaments

The infamous paired helical filaments (PHFs) of tau that sprawl across the brain in Alzheimer’s disease are the end products of a multiyear process. What drives tau to form these specific filaments in ...
The New York Times

How the Lisbon Funicular Works and Where It Crashed

São Pedro de Alcântara St. Upper stop BAIRRO ALTO Glória walk Where carriage crashed Lower stop The vintage Lisbon funicular that crashed on Wednesday, killing at least 16 people, lost control when ...
C&EN

Ginseng Glucosyl Oleanolate Suppresses Cervical Cancer via Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation In Vivo/Vitro

College of Food Science and Engineering, Jilin Agricultural University, Changchun 130018, China Jilin Province Innovation Center for Food Biological Manufacture, Jilin Agricultural University, ...
ascopubs.org

Integrated analysis of bulk and single-cell RNA sequencing data to identify an oxidative phosphorylation-based prognostic signature for lung adenocarcinoma.

Diagnostic performance of SHOX2 and RASSF1A gene methylation assays in malignant pleural effusion: A systematic review and meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
ascopubs.org

Clear and non-clear cell renal cell carcinomas and the ability to engage in oxidative phosphorylation.

Neoadjuvant lenvatinib plus pembrolizumab for resectable clear-cell renal cell carcinoma (PELUR): A prospective phase 2 study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.
Scientific Research Publishing

Zhang, Y., Wu, J., Jin, W., Shen, M., Yin, S., Lai, X.,

ABSTRACT: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the selective degeneration of dopaminergic neurons in the substantia nigra pars compacta, resulting in a ...
Geeky Gadgets

Master Microsoft Visio : Create Stunning Diagrams Like a Pro for Beginners 2025

Have you ever found yourself staring at a blank page, trying to organize a complex idea or process, but not knowing where to start? Whether it’s mapping out a workflow, designing an organizational ...
Women's Health

What Is Oxidative Stress? Causes And How To Reduce It, According To Experts

When you think of stress, you might turn to the family drama that kept you from sleeping at night or an overwhelming, heart-racing panic about an anxiety-inducing work project. However, there could be ...
ahajournals.org

Oxidative Stress Causes Mitochondrial and Electrophysiologic Dysfunction to Promote Atrial Fibrillation in Pitx2 +/− Mice

Although chromosome 4q25 variants near the PITX2 gene are the strongest genetic risk factor for atrial fibrillation, the mechanism(s) causing this proarrhythmia remains controversial. Pitx2 encodes a ...
The EMBO Journal

Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...
Frontiers

Oxidative stress: fundamentals and advances in quantification techniques

Oxidative species, generated endogenously via metabolism or from exogenous sources, play crucial roles in the body. At low levels, these species support immune functions by participating in ...