Ethnicity data are essential in understanding how different groups are impacted by different treatments/healthcare ...

The Canadian Task Force on Preventive Health Care’s (CTFPHC) mandate was to develop and disseminate evidence-based clinical ...

Background Proton pump inhibitors (PPIs) have been widely used for over 35 years. However, in recent decades, numerous adverse drug reactions (ADRs) have been reported, with evidence often ...

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Objectives Probability or risk outcome estimates tailored to individual patient characteristics can facilitate more personalised care, for example, regarding treatment. Yet, the uptake of prediction ...

Objectives To evaluate the performance of large language models (LLMs) in risk of bias assessment and to examine whether prompt engineering improves their accuracy and alignment with expert reasoning.

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Objective To examine the potential errors of a general large language model (LLM) (ie, Claude 3.5 Sonnet) on data extraction from randomised controlled trials (RCTs). Design and setting An empirical ...

The WHO defines health equity as ‘the absence of unfair, avoidable or remediable differences among groups of people based on various dimensions of inequality (eg, sex, gender, ethnicity, disability or ...

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Seeding trials —clinical studies designed primarily for marketing rather than scientific advancement—pose underappreciated risks to research integrity and patient safety. Sukhun Kang and colleagues ...