Background Pancreatic ductal adenocarcinoma (PDAC) is largely refractory to immune checkpoint blockade, owing to its ...

Background and aims Restoration of intestinal barrier integrity and function in inflammatory bowel disease (IBD) has been ...

We read with great interest the recent study by Lau et al , who reported distinct intrahepatic hepatitis B virus (HBV) ...

Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers due to its aggressive biology and ...

The trial by Yadav and colleagues concludes that proton pump inhibitors (PPIs) should be continued routinely after endoscopic ...

Background Endoscopic submucosal dissection (ESD) enables en bloc resection of early gastrointestinal cancers and provides ...

I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...

Introduction In a post-biosimilar era, where cost-effectiveness impacts therapeutic choices, filgotinib is an attractive option for UC. Whilst pivotal trial data and short-term real-world studies are ...

Introduction The comparable efficacy and safety of both IV and SC induction with guselkumab (GUS), a dual-acting IL-23p19 subunit inhibitor, in pts with moderately to severely active CD has been ...

Introduction The principle means of providing analgesia during colonoscopy in the UK is either through conscious sedation, or use of entonox, a fast-acting inhaled and self-administered analgesic gas.

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Background CDH1 is commonly mutated in sporadic diffuse gastric cancer (DGC) and germline CDH1 mutations underlie most cases of the cancer syndrome hereditary DGC. Objective We aimed to develop mouse ...