As of July 2025, Armas has no children, but Cruise has three: He adopted Bella, 32, and Connor, 30, with his second wife Nicole Kidman, and welcomed a daughter named Suri, 19, with ex-wife Katie Holmes. But after this comment, fans are wondering if Armas will become a mom, and if she’ll raise a family with Cruise.

She's also been linked to Manuel Anido Cuesta, the stepson of Miguel Diaz-Canel Bermudez, the President of Cuba. The pair have been photographed on different outings in Madrid and other locations, spending time with De Armas' dog, holding hands, and even sharing a kiss. Still, de Armas has yet to address that relationship publicly.

Katie Holmes appeared to show approval of ex-husband Tom Cruise's rumored romance with Ana de Armas by liking an Instagram post about the couple arriving together in London.