Apr 14, 2025 · The US Food and Drug Administration (FDA) has approved nivolumab (Opdivo, Bristol Myers Squibb) with ipilimumab (Yervoy, Bristol Myers Squibb) as a first-line treatment for adults with ...

Apr 23, 2025 · NICE has approved nivolumab plus ipilimumab for NHS use in patients with aggressive colorectal cancer, following new evidence of clinical benefit.

Jan 23, 2025 · Research has introduced daromun, therapeutic vaccines, and novel combinations for metastatic melanoma, reshaping the treatment landscape.

Apr 9, 2025 · The CRC indication is the latest approval for the combination therapy, which demonstrated improved PFS vs chemotherapy and nivolumab monotherapy.

Feb 7, 2025 · CORONADO, Calif. — Advances in adjuvant and neoadjuvant systemic therapies are continuing to improve recurrence-free and distant metastasis-free survival rates in patients with …

Jan 6, 2025 · The authors concluded that "as compared with ipilimumab monotherapy, nivolumab-containing therapies have continued to show a prolonged survival benefit in patients with advanced …

Jul 5, 2019 · For me, absent a rapidly growing tumor, high disease burden, or brain metastases, I would actually prefer to use the flip-dose ipilimumab/nivolumab regimen than the standard-dose ipilimumab ...

Aug 22, 2025 · Ipilimumab is a monoclonal antibody capable of blocking CTLA-4 signaling; it allows T-cell activation, proliferation, and amplification of T-cell-mediated immunity.

Aug 5, 2025 · Experts debate which patients with stage III dMMR colon cancer will benefit from the two treatment approaches.

Feb 14, 2025 · Patients receiving an immune checkpoint inhibitor for a neoplasm face an increased risk for rheumatoid arthritis, an observational study found.