Lactones are formed by lactonization, the intramolecular esterification of the corresponding hydroxycarboxylic acids. [2] Greek prefixes in alphabetical order indicate ring size.

Jul 30, 2025 · Lactonization is a chemical process that forms a lactone, a cyclic ester. This reaction involves the internal formation of a ring structure within a single molecule. The …

This lactonization reaction exhibits compatibility with tertiary, benzylic, allylic, methylene, and primary γ-C-H bonds, affording access to a wide range of structurally diverse lactones such as …

Lactonization refers to the process of synthesizing lactones, typically through the cyclization of hydroxycarboxylates, which can occur spontaneously in the presence of acids or via various …

Nov 10, 2025 · Lactonization is the chemical process responsible for creating lactones, which are cyclic esters. This reaction involves the internal restructuring of a single molecule to form a …

Here, we report a Pd-catalyzed β-C (sp 3)–H lactonization of aliphatic acids enabled by a mono- N -protected β-amino acid ligand.

Aug 4, 2023 · Herein we report a protocol for straightforward and general access to chiral γ -lactones via enantioselective oxidation of strong nonactivated primary and secondary C …

Jun 9, 2025 · Common strategies include ring-closing metathesis (RCM), cyclization reactions such as intramolecular esterification and lactonization, and enzymatic synthesis. The choice of …

Dec 11, 2019 · Here we report a Pd-catalysed β-C (sp3)–H lactonization of aliphatic acids enabled by a mono-N-protected β-amino acid ligand.

A lactone can be synthesised from a hydroxy acid through a process called intramolecular esterification or cyclisation. Intramolecular esterification, also known as cyclisation, is a …