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med's go on Instagram: "Goodpasture syndrome is caused by anti-GBM antibodies directed against type IV collagen in the basement membranes of both glomeruli and alveoli. Clinically, it presents with pulmonary hemorrhage (hemoptysis) and rapidly progressive glomerulonephritis, often with crescent formation on biopsy. Immunofluorescence shows a linear IgG pattern along the GBM, which distinguishes it from immune complex diseases that show granular patterns. It is a type II hypersensitivity reaction
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