Nucleophilic acyl substitution
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Nucleophilic Acyl Substitution (With Negatively Charged Nucleophiles) – Master Organic Chemistry
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masterorganicchemistry.com
The Fries rearrangement enables the Lewis-acid-promoted intramolecular transfer of an acyl group from an aryl ester to the aromatic ring, forming ortho- or para-acylphenols. Discovered by Karl Theophil Fries in the early 20th century, the reaction proceeds via activation of the ester by a Lewis acid followed by electrophilic aromatic substitution by the acyl group. Learn. Review. Repeat.
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The Fries rearrangement enables the Lewis-acid-promoted intramol…
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TikTokorganic_name_reactions
The Fries rearrangement enables the Lewis-acid-promoted intramolecular transfer of an acyl group from an aryl ester to the aromatic ring, forming ortho- or para-acylphenols. Discovered by Karl Theophil Fries in the early 20th century, the reaction proceeds via activation of the ester by a Lewis acid followed by electrophilic aromatic substitution by the acyl group. Learn. Review. Repeat.
0:16
The Fries rearrangement enables the Lewis-acid-promoted intramol…
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TikTokorganic_name_reactions
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