How KRAS function, and impact of KRAS mutation? #Code: 1203
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How KRAS function, and impact of KRAS mutation? #Code: 1203
Gist: Ras has three isoforms: HRAS, KRAS and NRAS. In this mutation is KRAS is more commonly associated with cancer, with 80% o the pancreatic cancer has mutation in G12, G13, and Q61. WT KRAS has two form inactive and active form. In active form is KRAS is bound with GDP. Once the tyrosine receptor kinase gets activated, it will cause Guanine ...
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